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James R Carlyle Selected Research

Infections

1/2021Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection.
1/2020Tetramer Immunization and Selection Followed by CELLISA Screening to Generate Monoclonal Antibodies against the Mouse Cytomegalovirus m12 Immunoevasin.
12/2019Mouse Cytomegalovirus m153 Protein Stabilizes Expression of the Inhibitory NKR-P1B Ligand Clr-b.
1/2019Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12.
1/2018The Tumor Necrosis Factor Superfamily Member RANKL Suppresses Effector Cytokine Production in Group 3 Innate Lymphoid Cells.
1/2017Interferon-Dependent Induction of Clr-b during Mouse Cytomegalovirus Infection Protects Bystander Cells from Natural Killer Cells via NKR-P1B-Mediated Inhibition.
1/2016Expansion and Protection by a Virus-Specific NK Cell Subset Lacking Expression of the Inhibitory NKR-P1B Receptor during Murine Cytomegalovirus Infection.
1/2015Modulation of Clr Ligand Expression and NKR-P1 Receptor Function during Murine Cytomegalovirus Infection.
1/2014Complexity and Diversity of the NKR-P1:Clr (Klrb1:Clec2) Recognition Systems.
5/2012Poxvirus infection-associated downregulation of C-type lectin-related-b prevents NK cell inhibition by NK receptor protein-1B.

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James R Carlyle Research Topics

Disease

10Infections
01/2021 - 05/2012
9Neoplasms (Cancer)
01/2023 - 07/2002
3Inflammation (Inflammations)
11/2022 - 10/2017
3Virus Diseases (Viral Diseases)
01/2019 - 05/2012
2COVID-19
06/2023 - 01/2022
1Pulmonary Alveolar Proteinosis
11/2022
1Pneumococcal Infections
11/2022
1Colitis
01/2021
1Lymphoma (Lymphomas)
01/2018
1Leukemia
01/2018
1Poxviridae Infections
05/2012
1Experimental Melanoma
06/2008
1Confusion (Bewilderment)
06/2006

Drug/Important Bio-Agent (IBA)

8LigandsIBA
12/2019 - 07/2002
3Interleukin-22 (IL-22)IBA
01/2021 - 10/2017
3C-Type Lectins (C-Type Lectin)IBA
01/2014 - 06/2008
2VaccinesIBA
06/2023 - 01/2022
2BNT162 VaccineIBA
06/2023 - 01/2022
2Transcription Factors (Transcription Factor)IBA
01/2023 - 01/2019
2Granzymes (Granzyme)IBA
01/2023 - 01/2016
2EnzymesIBA
01/2021 - 01/2019
2CytokinesIBA
01/2019 - 10/2017
1LipidsIBA
11/2022
1Surface-Active Agents (Surfactants)IBA
11/2022
1Pulmonary Surfactants (Pulmonary Surfactant)IBA
11/2022
1Fatty Acids (Saturated Fatty Acids)IBA
01/2021
1Acetyl-CoA CarboxylaseIBA
01/2021
1soraphen AIBA
01/2021
1Proteins (Proteins, Gene)FDA Link
01/2020
1Natural Killer Cell ReceptorsIBA
12/2019
1X-Box Binding Protein 1IBA
01/2019
1Glycoproteins (Glycoprotein)IBA
01/2019
1Inositol (Myoinositol)IBA
01/2019
1Chemokine ReceptorsIBA
01/2018
1Interleukin-17 (Interleukin 17)IBA
01/2018
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018
1Histocompatibility Antigens Class IIBA
01/2018
1InterferonsIBA
01/2017
1NK Cell Lectin-Like Receptor Subfamily BIBA
01/2015
1Pattern Recognition ReceptorsIBA
01/2015
1Membrane Proteins (Integral Membrane Proteins)IBA
05/2012
1Messenger RNA (mRNA)IBA
05/2012
1AntigensIBA
06/2008
1Peptides (Polypeptides)IBA
06/2008
1Isoantigens (Alloantigen)IBA
06/2006

Therapy/Procedure

2Therapeutics
01/2018 - 06/2008